The Medical Management Of Alzheimer s Disease - 2536 Words

Dementia is a syndrome of gradual onset and continuing decline of higher cognitive functioning (Alderman and Daly, 2005, p.1745). The term dementia is derived from Latin word demens (meaning without mind). Alzheimer’s disease (AD) is a most common form of dementia and a neurodegenerative disease with more than 25 million cases worldwide. The disease was first described by Alios Alzheimer a German physician in 1906 and published it in 1907 under the title â€Å"A characteristic serious disease of the cerebral cortex† (Cipriani, Dolciotti, Picchi Bonuccelli, 2009, p.277). This paper is going to reflect the pathophysiology, incidence, etiology, clinical manifestations, prognosis and a brief overview of the medical management of Alzheimer’s disease. According to U.S Census Bureau the total number of people with AD is projected to be 13.8 million by 2050 with 7.0 million people with 85 or older (AACN , 2013, p.17). According to Shampo, Kyle, Steensma the first known case was a 51 year old female who had progressive memory loss and she died after 5 years (2013). The implications of pharmacological treatment and physical therapy in a patient with AD will also be discussed in this paper. Pathophysiology The mechanism of the disease is largely unknown but the amyloid cascade hypothesis is the basis for the pathophysiology of AD. According to Armstrong â€Å"senile plaques (SPs) and neurofibrillary tangles (NFTs) have been regarded as the â€Å"signature† pathological lesions of Alzheimer’sShow MoreRelatedAlzheimer s Disease Is The Most Significant Risk Factor1074 Words   |  5 PagesAlzheimer s Disease Abstract Alzheimer’s disease currently represents the second leading cause of death in people older than 65 years residing in the modern world. 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It is basically a condition involving a pathological process along with a set of various symptoms; some easily noticeable whereas others quite difficult to detect, making their treatment process slower. (Healio.com, 2012) Nevertheless, the social and economic impacts followed by the diagnosis of the disease are generally quite drastic. Among the various types of diseases, certainRead MorePatients Health Of Medical Marijuana1733 Words   |  7 Pages Patients’ Health Utilizing Medical Marijuana Karen Mak Rutgers University Introduction to Research Methods, Fall 2016 Abstract The following study proposal would review the results of the overall health outcomes of patients who replaced pharmaceutical treatment with medical marijuana. The study will look at the improvements in meal consumption, Clinical Global Impression scores, Pittsburgh Agitation Scale, and the decrease in the symptom being monitored. 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Alzheimer s disease is the most common cause of dementia — a group of brain disorders that cause the loss of intellectual and social skills. In Alzheimer s disease, the